Figure 1 | Scientific Reports

Figure 1

From: Perfluorooctanoic acid exposure for 28 days affects glucose homeostasis and induces insulin hypersensitivity in mice

Figure 1

PFOA exposure decreased the protein expression of PTEN and modulated the PI3K-AKT signaling pathway.

(a) Representative western blotting images of liver lysates prepared from mice exposed to different doses of PFOA using antibodies against IRβ, p85, p110, phospho-PTEN (S380), total PTEN, phospho-PDK1 (S241), total PDK1, phospho-AKT (T380), phospho-AKT (S473) and total AKT protein. In figures reported here, p- indicates phospho- and t- indicates total, as mentioned above. (b) and (c) Relative fold change of band densities (n = 3). Data are means ± SE. Significantly different from control group (*p < 0.05, **p < 0.01).

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