Figure 3
Tolerance tests of mice after PFOA exposure.
(a) Glucose tolerance tests of mice exposed to PFOA at 5 mg/kg/d (n = 10). Mice were starved for 16 h and weighed (left). Serum insulin concentrations before and 30 min after glucose injection were analyzed (middle) and blood glucose concentrations were measured before and after glucose injection (right). (b) Insulin tolerance tests of mice exposed to PFOA at 5 mg/kg/d (n = 10). Mice were starved for 4 h and weighed (left). Glucose concentrations before insulin injection were measured (middle), with blood glucose concentration after insulin injection determined as a percentage of the concentration before injection (right). (c) Pyruvate tolerance tests of mice exposed to PFOA at 5 mg/kg/d (n = 10). Mice were starved for 16 h and weighed (left). Glucose concentration before pyruvate injection was measured (middle), with blood glucose concentration after pyruvate injection determined as a percentage of the concentration before injection (right). Data are means ± SE. Significantly different from control group (*p < 0.05, **p < 0.01).
