Figure 6

PFOA exposure altered serum protein profiles.
(a) Network of proteins related to diabetes differentially expressed in serum of mice exposed to PFOA. (b) Network of proteins related to liver functions or diseases differentially expressed in the serum of mice exposed to PFOA. (c) Western blot of serum from PFOA-exposed mice validated the iTRAQ results for ACAA1A, PON1 and SERPINA3K. Bar graph for relative fold change of band densities is presented below protein bands. Data are means ± SE. Significantly different from control group (*p < 0.05, **p < 0.01).