Figure 3 | Scientific Reports

Figure 3

From: Nano-Biomechanical Study of Spatio-Temporal Cytoskeleton Rearrangements that Determine Subcellular Mechanical Properties and Endothelial Permeability

Figure 3

AFM deflection images and time-lapse elastic modulus maps of live EC in response to (A, D) no simulation, (B, E) barrier-disrupting thrombin (1 unit/mL, 54 min) and (C, F) barrier-enhancing S1P (1 μM, 54 min); (G) quantification of live cell sub-cellular elastic modulus as a function of time in response to sequential thrombin (1 unit/mL) and S1P (1 μM) treatment.

n = 3 different cells are analyzed to generate the elastic modulus time-lapse responses. *p < 0.05.

Back to article page