Figure 9 | Scientific Reports

Figure 9

From: Antioxidant treatment enhances human mesenchymal stem cell anti-stress ability and therapeutic efficacy in an acute liver failure model

Figure 9

Assessment of secretion and expression of human hepatocyte growth factor (HGF) by human umbilical cord mesenchymal stem cells (hUCMSCs) in vitro and in vivo.

(a) In vitro measurements of HGF secretion by hUCMSCs with or without pre-treatment by edaravone or diethyl maleate (DEM). (b,c) Representative in vivo image of HGF-positive cells by infused hUCMSCs in the host mouse liver at day 7 post challenge. Eda10, 10 μM edaravone; Eda20, 20 μM edaravone; GL, D-galactosamine/LPS. “*” “***” mean significant changes (P < 0.05, 0.001) between indicated two groups, respectively. Bar: 50 μm.

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