Table 1 Reference databases used for data retrieval during the investigation.

From: Novel drug target identification for the treatment of dementia using multi-relational association mining

Database

Description

URL

Statistics

Data extracted

Clinical drug data

a database of publicly and privately supported clinical studies of human participants conducted around the world

www.clinicaltrials.gov

 

drug target

DrugBank

a bioinformatics and cheminformatics resource that combines detailed drug data with comprehensive drug target (i.e. sequence, structure and pathway) information

http://www.drugbank.ca/

4,092 unique drug targets

drug target

i2d

an on-line database of known and predicted mammalian and eukaryotic protein-protein interactions

http://ophid.utoronto.ca/

183,524 curated interactions for human

protein interaction

Reactome

a curated resource of core pathways and reactions in human biology.

http://www.reactome.org

1,597 for human

pathway

InterPro

an integrated database of predictive protein "signatures" used for the classification and automatic annotation of proteins and genome

http://www.ebi.ac.uk/interpro/

7,497 protein domains

protein domain

Gene Ontology

a relational database comprised of the GO terms as well as the annotations of genes and gene products to terms in the those ontologies

http://geneontology.org/

 

GO term