Table 1 Reference databases used for data retrieval during the investigation.
Database | Description | URL | Statistics | Data extracted |
Clinical drug data | a database of publicly and privately supported clinical studies of human participants conducted around the world | Â | drug target | |
DrugBank | a bioinformatics and cheminformatics resource that combines detailed drug data with comprehensive drug target (i.e. sequence, structure and pathway) information | 4,092 unique drug targets | drug target | |
i2d | an on-line database of known and predicted mammalian and eukaryotic protein-protein interactions | 183,524 curated interactions for human | protein interaction | |
Reactome | a curated resource of core pathways and reactions in human biology. | 1,597 for human | pathway | |
InterPro | an integrated database of predictive protein "signatures" used for the classification and automatic annotation of proteins and genome | 7,497 protein domains | protein domain | |
Gene Ontology | a relational database comprised of the GO terms as well as the annotations of genes and gene products to terms in the those ontologies | Â | GO term |