Table 4 List of predicted drug targets with UniProt ID, Official gene symbol, Gene name and Degree centrality.

From: Novel drug target identification for the treatment of dementia using multi-relational association mining

UniProt ID

Official Gene Symbol

Gene Name

Degree

P78352

DLG4

discs, large homolog 4 (Drosophila)

18

P17612

PRKACA

protein kinase, cAMP-dependent, catalytic, alpha

17

P28482

MAPK1

mitogen-activated protein kinase 1

16

P05771

PRKCB

protein kinase C, beta

14

Q05655

PRKCD

protein kinase C, delta

13

P31749

AKT1

v-akt murine thymoma viral oncogene homolog 1

12

P68400

CSNK2A1

casein kinase 2, alpha 1 polypeptide pseudogene; casein kinase 2, alpha 1 polypeptide

11

P68400

CSNK2A1P

casein kinase 2, alpha 1 polypeptide pseudogene; casein kinase 2, alpha 1 polypeptide

11

Q96RR4

CAMK2A

calcium/calmodulin-dependent protein kinase kinase 2, beta

10

P27361

MAPK3

hypothetical LOC100271831; mitogen-activated protein kinase 3

9

Q8TD19

NEK9

NIMA (never in mitosis gene a)- related kinase 9

9

Q05513

PRKCZ

protein kinase C, zeta

7

Q9UQM7

CAMK2a

calcium/calmodulin-dependent protein kinase II alpha

7

P25098

ADRBK1

adrenergic, beta, receptor kinase 1

6

Q02156

PRKCE

protein kinase C, epsilon

6

O00141

SGK1

serum/glucocorticoid regulated kinase 1

5

P45983

MAPK8

mitogen-activated protein kinase 8

5

P51812

RPS6KA3

ribosomal protein S6 kinase, 90kDa, polypeptide 3

5

Q15831

STK11

serine/threonine kinase 11

5

Q96L34

MARK4

MAP/microtubule affinity-regulating kinase 4

5

Q9Y6E0

STK24

serine/threonine kinase 24 (STE20 homolog, yeast)

5

P19784

csnk2a2

casein kinase 2, alpha prime polypeptide

4

P23443

RPS6KB1

ribosomal protein S6 kinase, 70kDa, polypeptide 1

4

P34947

GRK5

G protein-coupled receptor kinase 5

4

O94985

CLSTN1

calsyntenin 1

3

P30411

BDKRB2

bradykinin receptor B2

3

P43250

GRK6

G protein-coupled receptor kinase 6

3

Q15418

RPS6KA1

ribosomal protein S6 kinase, 90kDa, polypeptide 1

3

Q16512

PKN1

protein kinase N1

3

Q16659

MAPK6

mitogen-activated protein kinase 6

3

O75582

RPS6KA5

ribosomal protein S6 kinase, 90kDa, polypeptide 5

2

Q99683

MAP3K5

mitogen-activated protein kinase kinase kinase 5

2

Q9NSB8

HOMER2

homer homolog 2 (Drosophila)

2

Q9NSC5

HOMER3

homer homolog 3 (Drosophila)

2