Table 4 List of predicted drug targets with UniProt ID, Official gene symbol, Gene name and Degree centrality.
UniProt ID | Official Gene Symbol | Gene Name | Degree |
|---|---|---|---|
P78352 | DLG4 | discs, large homolog 4 (Drosophila) | 18 |
P17612 | PRKACA | protein kinase, cAMP-dependent, catalytic, alpha | 17 |
P28482 | MAPK1 | mitogen-activated protein kinase 1 | 16 |
P05771 | PRKCB | protein kinase C, beta | 14 |
Q05655 | PRKCD | protein kinase C, delta | 13 |
P31749 | AKT1 | v-akt murine thymoma viral oncogene homolog 1 | 12 |
P68400 | CSNK2A1 | casein kinase 2, alpha 1 polypeptide pseudogene; casein kinase 2, alpha 1 polypeptide | 11 |
P68400 | CSNK2A1P | casein kinase 2, alpha 1 polypeptide pseudogene; casein kinase 2, alpha 1 polypeptide | 11 |
Q96RR4 | CAMK2A | calcium/calmodulin-dependent protein kinase kinase 2, beta | 10 |
P27361 | MAPK3 | hypothetical LOC100271831; mitogen-activated protein kinase 3 | 9 |
Q8TD19 | NEK9 | NIMA (never in mitosis gene a)- related kinase 9 | 9 |
Q05513 | PRKCZ | protein kinase C, zeta | 7 |
Q9UQM7 | CAMK2a | calcium/calmodulin-dependent protein kinase II alpha | 7 |
P25098 | ADRBK1 | adrenergic, beta, receptor kinase 1 | 6 |
Q02156 | PRKCE | protein kinase C, epsilon | 6 |
O00141 | SGK1 | serum/glucocorticoid regulated kinase 1 | 5 |
P45983 | MAPK8 | mitogen-activated protein kinase 8 | 5 |
P51812 | RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | 5 |
Q15831 | STK11 | serine/threonine kinase 11 | 5 |
Q96L34 | MARK4 | MAP/microtubule affinity-regulating kinase 4 | 5 |
Q9Y6E0 | STK24 | serine/threonine kinase 24 (STE20 homolog, yeast) | 5 |
P19784 | csnk2a2 | casein kinase 2, alpha prime polypeptide | 4 |
P23443 | RPS6KB1 | ribosomal protein S6 kinase, 70kDa, polypeptide 1 | 4 |
P34947 | GRK5 | G protein-coupled receptor kinase 5 | 4 |
O94985 | CLSTN1 | calsyntenin 1 | 3 |
P30411 | BDKRB2 | bradykinin receptor B2 | 3 |
P43250 | GRK6 | G protein-coupled receptor kinase 6 | 3 |
Q15418 | RPS6KA1 | ribosomal protein S6 kinase, 90kDa, polypeptide 1 | 3 |
Q16512 | PKN1 | protein kinase N1 | 3 |
Q16659 | MAPK6 | mitogen-activated protein kinase 6 | 3 |
O75582 | RPS6KA5 | ribosomal protein S6 kinase, 90kDa, polypeptide 5 | 2 |
Q99683 | MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | 2 |
Q9NSB8 | HOMER2 | homer homolog 2 (Drosophila) | 2 |
Q9NSC5 | HOMER3 | homer homolog 3 (Drosophila) | 2 |