Figure 5
From: DW-F5: A novel formulation against malignant melanoma from Wrightia tinctoria
DW-F5 down-regulates key molecules crucial for melanoma survival.
(a–g) Tumour tissues of mice treated with DW-F5 shows marked reduction in the expression of molecules such as (a) BRAF, (b) p-ERK1/2, (c) Brn-2, (d) β-catenin, (e) MITF-M, (f) p-p65 and (g) Bcl-2 as assessed by IHC.
