Figure 2
From: Pentamethylquercetin (PMQ) reduces thrombus formation by inhibiting platelet function
PMQ- or aspirin-treated mice were protected from microvascular thrombosis.
Mice were pre-treated with vehicle, 10 mg/kg PMQ, 20 mg/kg PMQ, or 50 mg/kg aspirin for 30 min prior to injury with intravenous injection of collagen (3.57 mg/kg) and epinephrine (0.143 mg/kg). (A) PMQ was effective in preventing collagen-epinephrine-induced thromboembolic death (n = 10). *** p < 0.001 vs. vehicle, ### p < 0.001 vs. control, NS not significant vs. model. (B) Representative sections of H&E-stained lung sections from mice treated as labeled. Magnification: ×200.
