Figure 1 | Scientific Reports

Figure 1

From: Inhibition of hypoxia inducible factors combined with all-trans retinoic acid treatment enhances glial transdifferentiation of neuroblastoma cells

Figure 1

HIF1A and EPAS1 gene expression is associated with poor survival in patients with NBL.

Kaplan-Maier analysis with patients grouped by the optimal cut-off (calculated using the R2 web tool) of expression of HIF1A and EPAS1 for overall survival and relapse-free survival rates, in 88 patients with NBL (Versteeg dataset) and 102 International Neuroblastoma Staging System stage 4 patients with MYCN not amplified (Seeger dataset). The overall survival data of the Seeger dataset were not available. The “raw P” indicates the uncorrected p-value, whereas the “bonf P” indicates the p-value corrected for multiple tests according the Bonferroni method.

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