Table 1 Antibody responses induced by the H7N9/AA ca reassortant virus in mice, guinea pigs, and ferrets a

From: A live attenuated vaccine prevents replication and transmission of H7N9 virus in mammals

Animal

Mean antibody titers (range)

Pre-test

Dose 1

Dose 2

HI

NT

HI

NT

HI

NT

Mouse

<10

<10

64 (40–80)

80 (80–80)

403 (320–640)

806 (640–1280)

Ferret

<10

<10

101 (80–160)

80 (40–160)

320 (320–320)

254 (160–320)

Guinea pig

<10

<10

64 (40–80)

80 (80–80)

507 (320–640)

254 (160–320)

  1. aThe indicated animals were inoculated with one or two doses, with a 3-week interval, of 106 EID50 of the H7N9/AAca virus. Three weeks after dose 1 or dose 2, sera were collected to determine HI and NT antibody titers by using the homologous wild-type H7N9 virus.
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