Figure 7

Fish oil supplementation suppresses metabolic endotoxemia and low grade inflammation.
Twenty-month-old WT mice previously received a high n-6 PUFA (10% corn oil) diet were supplemented with n-3 PUFA (5% corn oil+5% fish oil) for 2 months. Serum samples were collected before and after the supplementation from the supplemented and control mice and subjected to analysis for markers of metabolic endotoxemia (LPS, LBP, sCD14) (a) and chronic inflammation (TNF-α, IL-1β, IL-6) (b). Data are expressed as mean ± SE. Significance was determined by unpaired two-tailed student T-test. *P < 0.05; **P < 0.01; ***P < 0.001. CO, corn oil; FO, fish oil.