Figure 5 | Scientific Reports

Figure 5

From: Radiation quality-dependence of bystander effect in unirradiated fibroblasts is associated with TGF-β1-Smad2 pathway and miR-21 in irradiated keratinocytes

Figure 5

TGF-β1-Smad2 pathway and miR-21 regulated each other.

Panel a, the effect of SB431542 on the miR-21 expression level in HaCaT cells irradiated with α-particles. * P < 0.05 compared with the relative control. Panel b, the effect of overexpression of miR-21 on the phosphorylation of Smad2 in HaCaT cells upon α-irradiation. Panel c, downregualtion of miR-21 in HaCaT cells alone induced phosphorylation of Smad2.

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