Table 2 Dose relation analysis for new-onset AF.
Variables | No. of patients | No. of patients with AF | Incidence rate (per 1000 person-yrs) | Adjusted HR | (95% CI) | P value |
|---|---|---|---|---|---|---|
Non-users (<28 days) | 11,162 | 782 | 9.6 | |||
RAS blockers users | 11,162 | 693 | 7.2 | 0.64 | (0.58-0.71) | <0.001 |
28-365 days | 2,626 | 175 | 8.8 | 0.77 | (0.65-0.90) | 0.002 |
>365 days | 8,536 | 518 | 6.8 | 0.60 | (0.54-0.67) | <0.001 |
pure ACEIs users | 2,744 | 155 | 7.5 | 0.80 | (0.67-0.94) | 0.007 |
pure ARBs users | 1,747 | 84 | 5.4 | 0.64 | (0.51-0.80) | <0.001 |
mixed users | 6,671 | 454 | 7.6 | 0.77 | (0.69-0.86) | <0.001 |
