Figure 4
Baseline blood glucose levels after a six hours fasting period did not differ significantly between treatment groups
((a), one-way ANOVA/Tukey’s). Overall, the results of an oral glucose tolerance test were not influenced by long-term ghrelin agonist treatment (AUC = area under the curve, (b–e)). In the second test, animals from the high GI + ghrelin group were treated with the ghrelin agonist immediately before the glucose tolerance test and showed significantly higher blood glucose levels than in the first test (p = 0.010, t-test for paired samples, (b) and (d)). Both serum acyl ((f), p = 0.020, Kruskal-Wallis/Dunn’s) and desacyl ghrelin ((h), p = 0.020, ANOVA/Tukey’s) levels measured after a 6-hour fasting period were significantly higher in animals treated with the ghrelin agonist. There were no significant differences in serum insulin levels in the same samples ((g), one-way ANOVA/Tukey’s 4.7). Bars indicate SEM.
