Figure 5 | Scientific Reports

Figure 5

From: Ghrelin agonist does not foster insulin resistance but improves cognition in an Alzheimer’s disease mouse model

Figure 5

Animals treated with a ghrelin agonist showed a significantly lower amount of phosphorylated IRS (pIRS Ser636), which has been shown to be associated with impaired glucose tolerance

((a), p = 0.039, nonparametric Kolmogorov-Smirnov test). However, we did not detect any significant differences in hippocampal tissue between the high GI and high GI + ghrelin agonist groups for synaptophysin (c), pSAP/JNK (d), TNF-α (e) or PSD-95 (f). Bars indicate SEM.

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