Figure 4 | Scientific Reports

Figure 4

From: Identification of the long non-coding RNA H19 in plasma as a novel biomarker for diagnosis of gastric cancer

Figure 4

Evaluation of H19 levels in GC cell lines and plasma samples of patients with GC, GC cell lines or culture medium.

(A) Plasma H19 levels in 70 consecutive GC patients and 70 healthy controls. Using a real-time RT-PCR assay, difference in plasma H19 expression between GC patients and normal healthy controls was determined (P < 0.0001). (B) The ROC curve analysis for discriminative ability between GC cases and normal controls (AUC = 0.838, sensitivity: 0.829, specificity: 0.729). (C) The expression of H19 in GC cell lines. Differential expressions of H19 in GC cell lines were compared with GES-1 cells (P < 0.05, compared with GES-1). (D) The expression of H19 in GC cell culture medium incubated for 0, 1, 2 days (P < 0.05, compared with GES-1).

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