Table 3 A detailed description of the 21 significantly regulatory cell death genes.

From: Network-based survival-associated module biomarker and its crosstalk with cell death genes in ovarian cancer

Gene symbol

Entrez gene/miRBase ID

Gene name

Reference

P value

BCL2L1

598

BCL2-like 1

39

0.015

CCND3

896

Cyclin D3

-

0.022

FASLG

356

Fas ligand (TNF superfamily, member 6)

53

0.023

FOS

2353

FBJ murine osteosarcoma viral Oncogene homolog

54

5.19E-3

IFNG

3458

Interferon, gamma

-

6.34E-4

IRS1

3667

Insulin receptor substrate 1

55

0.047

IRS2

8660

Insulin receptor substrate 2

-

0.022

MAPK14

1432

Mitogen-activated protein kinase 14

-

0.026

NFKB1

4790

Nuclear factor of kappa light polypeptide gene enhancer in B-cells1

56

0.076

PIK3CA

5290

Phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha

57

9.87E-3

PIK3R1

5295

Phosphoinositide-3-kinase, regulatory subunit 1 (alpha)

-

1.34E-5

PIK3R3

8503

Phosphoinositide-3-kinase, regulatory subunit 3 (gamma)

58

0.020

PRKCQ

5588

Protein kinase C, theta

-

3.33E-9

PTPN13

5783

Protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase)

-

0.082

RELA

5970

V-rel avian reticuloendotheliosis viral oncogene homolog A

59

0.091

SRC

6714

SRC proto-oncogene, non-receptor tyrosine kinase

60

0.023

STAT3

6774

Signal transducer and activator of transcription 3 (acute-phase response factor)

61,62

0.028

 

hsa-miR-335-5p

 

24,40

6.52E-4

 

hsa-miR-34b-3p

 

-

0.063

 

hsa-miR-34c-5p

 

63

0.097

 

hsa-miR-99b-3p

 

-

0.078