Figure 3
From: Rapid endosomal escape of prickly nanodiamonds: implications for gene delivery
Evidence of nanodiamonds’ rupturing the endosomal compartment, causing their cytosol release.
(a) Schematic illustration of the experimental design to identify how nanodiamonds escape the endosomal compartments. (b) Typical TEM images showing distribution of SiO2 in HepG2 cells after cells’ incubation with SiO2 only in serum-free medium for 24 hours. (c) Typical TEM images showing distribution of nanodiamonds in HepG2 cells after cells’ incubation with nanodiamonds only in serum-free medium for 24 hours. (d) Typical TEM images showing distribution of SiO2 + NDs in HepG2 cells after cells’ incubation with the mixed nanoparticles in serum-free medium for 24 hours.
