Table 1 Characteristics of eligible studies included in the meta-analysis.
First author | Year | Country | Ethnicity | Form of Disease | Sample size (Case/Control) | Distribution of genotypes and alleles | Smoking status | Genotyping method | Quality scores | |||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Case | Control | |||||||||||||
5A/5A/5A/6A/6A/6A | 5A | 6A | 5A/5A/5A/6A/6A/6A | 5A | 6A | |||||||||
Itagaki | 2004 | Japan | Asian | CP | 205/142 | 5/58/142 | 68 | 342 | 4/38/100 | 46 | 238 | Non-smokers | TaqMan | 31 |
Itagaki | 2004 | Japan | Asian | AgP | 37/142* | 0/17/20 | 17 | 57 | 4/38/100 | 46 | 238 | Non-smokers | TaqMan | 31 |
Astolfi | 2006 | Brazil | Mixed | CP | 90/103 | 19/52/19 | 90 | 90 | 8/70/25 | 86 | 120 | Non-smokers | PCR-RFLP | 29 |
Kobayashi | 2009 | Japan | Asian | CP | 147/303 | — | 37 | 257 | — | 72 | 534 | S/N | DNA chip & PCR | 29 |
Kobayashi | 2009 | Japan | Asian | AgP | 172/303* | — | 58 | 286 | — | 72 | 534 | S/N | DNA chip & PCR | 29 |
Loo | 2011 | China | Asian | CP | 280/250 | 154/115/11 | 423 | 137 | 100/135/15 | 335 | 165 | Non-smokers | PCR-RFLP | 28 |
Letra | 2012 | Brazil | Mixed | CP | 93/299 | — | 117 | 69 | — | 356 | 242 | S/N | TaqMan | 30 |
Letra | 2012 | USA | Caucasian | CP | 67/202 | — | 78 | 56 | — | 193 | 211 | S/N | TaqMan | 30 |
Li | 2012 | China | Asian | CP | 122/532 | 75/44/3 | 194 | 50 | 213/283/36 | 709 | 355 | S/N | PCR-RFLP | 27 |
