Figure 3 | Scientific Reports

Figure 3

From: Low-molecular-mass secretome profiling identifies HMGA2 and MIF as prognostic biomarkers for oral cavity squamous cell carcinoma

Figure 3

Informatics analysis flowchart for the discovery of LMr OSCC biomarkers.

The LMr secretome profiles obtained from the five OSCC cancer cell lines were combined together to find proteins detected in any one of the five cell lines (A) or detected commonly in all five cell lines (B). The list of proteins generated in (A) was then processed to identify “true” LMr proteins and compare with OSCC tissue gene expression data available in the public domain (upregulated mRNAs) for the discovery of LMr OSCC biomarkers.

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