Figure 6 | Scientific Reports

Figure 6

From: Low-molecular-mass secretome profiling identifies HMGA2 and MIF as prognostic biomarkers for oral cavity squamous cell carcinoma

Figure 6

Attenuation of OSCC cell migration and invasiveness by HGMA2- and MIF-specific RNAi.

(A) Western blot analysis of HGMA2 and MIF expression in lysates from SCC4 and SCC25 cells transfected with HMGA2-specific RNAi (si-HGMA2), MIF-specific RNAi (si-MIF), or the scrambled sequence control RNAi. (B) Cell proliferation assays for SCC4 and SCC25 cells transfected with si-HMGA2, si-MIF or the scrambled sequence control RNAi (si-CTL) for 48 and 72 h, respectively. (C and D) Cell migration and invasion assays for SCC4 and SCC25 cells transfected with si-HMGA2, si-MIF or si-CTL for 48 and 72 h, respectively. (E and F) Slides showing representative results of our cell migration and invasion assays.

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