Table 1 List of 33 potential OSCC biomarkers derived from LMr secretome.

From: Low-molecular-mass secretome profiling identifies HMGA2 and MIF as prognostic biomarkers for oral cavity squamous cell carcinoma

Protein (Gene symbol)	MW(Da)	Detectable in LMr secretome					Upregulated in microarray dataset									Secretory pathway predicition
Protein (Gene symbol)	MW(Da)	OC3	OECM1	SAS	SCC4	SCC25	E-MEXP-44	E-TABM-302	E-UMCU-11	GDS1062	GDS1584	GDS2520	E-GEOD-13601	GSE9349	GSE9844	SingnalP	SecrectomeP*	TMHMM
Beta-defensin 2 (DEFB4)	7038		+										+		+	Y	Y	Y
Ubiquitin (RPS27A)	8565	+	+		+	+	+								+	N	Y	N
Cyclin-dependent kinases regulatory subunit 1 (CKS1B)	9660	+	+		+	+	+					+			+	N	N	N
Small nuclear ribonucleoprotein F (SNRPF)	9725	+	+	+	+		+									N	N	N
Cyclin-dependent kinases regulatory subunit 2 (CKS2)	9860	+			+	+	+						+	+		N	N	N
C-X-C motif chemokine 11 (CXCL11)	10365	+	+			+		+			+		+		+	Y	N	Y
C-C motif chemokine 20 (CCL20)	10762	+	+	+		+							+		+	Y	Y	N
C-X-C motif chemokine 10 (CXCL10)	10882	+	+		+	+					+		+		+	Y	Y	Y
Growth-regulated alpha protein (CXCL1)	11302	+	+	+	+	+					+		+		+	Y	Y	N
C-X-C motif chemokine 2 (CXCL2)	11389	+	+	+		+									+	Y	Y	N
High mobility group protein HMGI-C (HMGA2)	11832	+			+	+					+				+	N	Y	N
Interferon-induced transmembrane protein 1 (IFITM1)	13965	+	+	+	+	+					+					N	Y	Y
Histone H2A type 2-A (HIST2H2AA3)	14096	+	+	+	+	+						+	+		+	N	N	N
Galectin-1 (LGALS1)	14716	+	+	+	+	+					+	+				N	N	N
Thymosin beta-10 (TMSB10)	5026	+	+	+	+	+							+			N	Y	N
Apolipoprotein C-I (APOC1)	9332	+	+	+	+	+					+					Y	Y	N
C-C motif chemokine 5 (CCL5)	9990	+	+		+	+					+		+			Y	Y	Y
BolA-like protein 2 (BOLA2)	10116	+	+	+	+	+	+						+			N	Y	N
60S ribosomal protein L37a (RPL37A)	10275	+			+	+				+						N	Y	N
Protein S100-P (S100P)	10400	+	+	+	+	+							+			N	Y	N
10 kDa heat shock protein, mitochondrial (HSPE1)	10932	+	+	+	+	+						+				N	Y	N
Protein S100-A2 (S100A2)	11117	+	+	+	+	+							+			N	N	N
Apolipoprotein A-II (APOA2)	11175	+								+						Y	Y	N
C-X-C motif chemokine 3 (CXCL3)	11343	+	+	+	+	+									+	Y	Y	N
C-X-C motif chemokine 6 (CXCL6)	11898				+										+	Y	Y	N
Transcription elongation factor B polypeptide 1 (TCEB1)	12473	+	+	+	+	+	+									N	N	N
Macrophage migration inhibitory factor (MIF)	12477	+	+	+	+	+							+			N	Y	N
Lymphocyte antigen 6D (LY6D)	13286	+			+	+							+			Y	N	Y
Histone H2A.V (H2AFV)	13509	+	+	+	+	+									+	N	Y	N
Serum amyloid A protein (SAA1)	13533	+			+	+		+			+				+	Y	Y	N
Histone H2B type 1-C/E/F/G/I (HIST1H2BC)	13893	+	+	+	+	+	+					+				N	N	N
Activated RNA polymerase II transcriptional coactivator p15 (SUB1)	14396	+	+	+	+	+							+			N	Y	N
Fatty acid-binding protein, adipocyte (FABP4)	14719					+					+					N	Y	N

^*Y, NN-score ≥0.5; N, NN-score <0.5.

Back to article page

Table 1 List of 33 potential OSCC biomarkers derived from LMr secretome.

Search

Quick links