Table 1 Characteristics of studies included in meta-analysis.

From: Influence of carbapenem resistance on mortality of patients with Pseudomonas aeruginosa infection: a meta-analysis

Author (year)

Country

Type of study

Sample size, n: CRPA vs. CSPA

Sites of infection

Definition of resistance

Type of carbapenem

Carbapenem Resistance

NOS score

Krcmery (1996)15

Slovakia

Retrospective cohort

10 vs. 91

Bacteremia

NA

Imipenem

9.9%

5

Cofsky (2002)16

USA

Retrospective case-control

10 vs. 10

Any infection

NA

Carbapenem

NA

9

Kang (2005)17

Korea

Retrospective cohort

28 vs. 162

Bacteremia

NCCLS

Imipenem

14.7%

7

Marra (2005)18

USA

Retrospective cohort

16 vs. 72

Bacteremia

NA

Imipenem

18.2%

7

Gasink (2006)8

USA

Retrospective cohort

872

Any infection or colonization

NCCLS

Imipenem

NA

7

Lautenbach (2006)19

USA

Retrospective cohort

135 vs. 719

Any infection or colonization

CLSI

Imipenem

15.8%

7

Eagye (2009)20

USA

Retrospective case-control

58 vs. 125

Any infection or colonization

NA

Meropenem

NA

9

Lautenbach (2010)21

USA

Retrospective cohort

253 vs. 2289

Any infection or colonization

CLSI

Imipenem

10.0%

9

Suárez (2010)22

Spain

Retrospective cohort

33 vs. 88

Bacteremia

CLSI (2005)

Carbapenem

27.3%

9

Joo (2011)13

Korea

Retrospective cohort

46 vs. 156

Bacteremia

NA

Imipenem

22.8%

9

Babu (2011)23

India

Prospective cohort

24 vs. 86

Any infection

CLSI (2007)

Imipenem

21.8%

5

Pena (2012)24

Spain

Prospective cohort

145 vs. 487

Bacteremia

CLSI

Carbapenem

22.9%

9

Tuon (2012)25

Brazil

Retrospective cohort

29 vs.48

Bacteremia

CLSI (2010)

Carbapenem

37.7%

9

Hattemer (2013)14

USA

Retrospective cohort

13 vs. 137

Bacteremia

CLSI (2012)

Carbapenem

8.7%

9

Lin (2014)26

China

Retrospective case-control

82 vs. 82

Any infection or colonization

CLSI (2011)

Carbapenem

NA

7

Dantas (2014)27

Brazil

Retrospective cohort

55 vs. 65

Bacteremia

CLSI

Carbapenem

45.8%

7

Kim (2014)28

Korea

Retrospective cohort

118 vs. 116

Bacteremia

CLSI (2008)

Carbapenem

50.4%

9

  1. Abbreviations: CRPA, carbapenem-resistant Pseudomonas aeruginosa; CSPA, carbapenem-susceptible Pseudomonas aeruginosa; NOS, Newcastle-Ottawa Scale; NA, not available; NCCLS, National Committee for Clinical Laboratory Standards; CLSI, Clinical and Laboratory Standard Institute.