Figure 3 | Scientific Reports

Figure 3

From: Herbal formula, Scutellariae radix and Rhei rhizoma attenuate dimethylnitrosamine-induced liver fibrosis in a rat model

Figure 3

(A) Typical 2-DE protein profiles of rat liver samples. (B) Close-up figures show changes in the levels of protein expression among various groups. Each spot volume was determined and their intensities were quantified by sliver-stained 2-DE (Nonlinear Progenesis software).The protein spots found to be significantly different in volume are indicated by Arabic numbers. (C) The protein levels of COMT, β-tubulin and K8 were assessed by Western blot analysis. GAPDH was used as an internal control and the relative expression to GAPDH is shown at the bottom. (D) Top-ranked pathways from the GeneGO MetaCore™ pathway analysis. Pathways were ranked according to p values and bars represent the inverse log of the p value. (E) Biological network analyses of differentially expressed proteins using MetaCore™ mapping tools. Nodes represent proteins and lines between the nodes indicate direct protein–protein interactions. The various proteins on this map are indicated by different symbols representing the functional class of the proteins.

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