Figure 3 | Scientific Reports

Figure 3

From: Inhibition of P-glycoprotein Gene Expression and Function Enhances Triptolide-induced Hepatotoxicity in Mice

Figure 3

Effects of mdr1a-siRNA and tariquidar on triptolide toxicokinetics in mice.

The NC-siRNA or mdr1a-siRNA (15 nM) was intravenously injected 2 days and tariquidar (10 mg/kg) was intravenously given 20 min prior to the injection of triptolide at a dose of 1 mg/kg. The blood samples were collected at scheduled time points. Data are presented as mean ± SD (n = 5).

Back to article page