Figure 3 | Scientific Reports

Figure 3

From: INC280, an orally available small molecule inhibitor of c-MET, reduces migration and adhesion in ovarian cancer cell models

Figure 3

INC280 inhibits HGF-stimulated chemotactic and random migration.

Boyden chamber assays were used to assess chemotactic migration toward serum in 3 cell lines (A). Data represents the mean from 3 separate experiments ± standard deviation. * p < 0.05, ** p < 0.005, ns(+) indicates not significant when 3 experiments are combined, although each individual assay was significant. ns, not statistically significant. Data from individual assays using CaOV3 cells has been included as Supplementary Figure 7. B) Migration plots of individual SKOV3 cells over 26 hrs on cell-derived matrix. Data is from single representative experiment (n = 3).

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