Table 2 Main results of the meta-analysis of the pooled OR.

From: Lack of an Association between the SDF-1 rs1801157 Polymorphism and Coronary Heart Disease: A Meta-Analysis

Variable

Cases/controls (n)

ORb (95% CI) Ph value

Allele(A vs.G)

Homozygote(AA vs.GG)

Heterzygote(AG vs.GG)

Dominant(AA/AG vs.GG)

Recessive(AA vs.AG/GG)

All subjects

4656/2654

0.914(0.704–1.186)0.499

0.903(0.516–1.581)0.722

0.854(0.675–1.081)0.189

0.865(0.654–1.145)0.312

0.982(0.609–1.583)0.939

Primary outcome

 CHD

3896/1892

1.056(0.826–1.351)0.663

1.223(0.716–2.090)0.461

1.053(0.924–1.199)a0.441

1.036(0.814–1.320)0.772

1.244(0.766–2.021)0.377

 MI

760/762

0.674(0.571–0.797)a0.000

0.473(0.297–0.753)a0.002

0.640(0.517–0.792)a0.000

0.618(0.503–0.759)a0.000

0.580(0.368–0.916)a0.019

Ethnicity

 Asian

1236/1410

0.903(0.500–1.630)0.735

0.830(0.237–2.905)0.771

0.839(0.553–1.271)0.407

0.855(0.477–1.534)0.600

0.905(0.304–2.692)0.858

 Caucasian

3420/1244

0.916(0.712–1.179)0.497

0.922(0.661–1.285)a0.632

1.140(0.929–1.398)0.378

0.866(0.615–1.219)0.408

0.971(0.698–1.351)a0.862

  1. Ph, P value for Cochran’s Q test for between-study heterogeneity in each genetic comparison model. a: A fixed effects model was used when the P value for Cochran’s Q test for heterogeneity >0.1. Otherwise, a random effects model was used. b: Crude OR.
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