Figure 9 | Scientific Reports

Figure 9

From: Host Responses and Regulation by NFκB Signaling in the Liver and Liver Epithelial Cells Infected with A Novel Tick-borne Bunyavirus

Figure 9

Differential effect of NSs on the activation of NFκB and IFN-β promoter activities.

HepG2 (A, B, C and D) and HeLa (E and F) cells were co-transfected with plasmids expressing NSs , pGL3-IFN-β-Luc (A, C, E), or pGL3 Ig k-Luc (B, D, F) along with pRL8 for 24 hrs , followed by stimulation with 50 μg of poly (I:C)/ml for another 6 hrs. Cell lysates were subjected to lysis and the lysates were measured for luciferase activities. The results are shown as absolute RLU (A, B) or activation fold (C, D, E and F).

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