Figure 1

Line plot displaying mean age- and sex-adjusted relative telomere length (RTL) per stages of chronic kidney disease (CKD) defined by the Kidney Disease Outcomes Quality Initiative (KDOQI) guidelines.
Error bars refer to the 95% confidence interval (CI). Overall p-values for comparison between GFR groups are obtained from general linear regression models for each study. RTL values of CRISIS and MMKD are not directly comparable as different DNA extraction methods were used in the two studies that have an influence on the measured values39. However, each of the studies can be interpreted on its own. Numbers near the lines represent the number of patients in the respective chronic kidney disease stages.