Figure 3

A schematic representing the metabolic pathways of the glycolysis and gluconeogenesis.
The squared enzymatic proteins were all up-regulated in the CWP group compared to the healthy subjects except creatine kinase which was down-regulated. This could be explained by a higher dependence and therefore a higher strain on the glycolysis to provide energy for the skeletal muscle resulting in an accumulation of Pi, H+, pyruvate and lactate.