Figure 3 | Scientific Reports

Figure 3

From: Protein alterations in women with chronic widespread pain – An explorative proteomic study of the trapezius muscle

Figure 3

A schematic representing the metabolic pathways of the glycolysis and gluconeogenesis.

The squared enzymatic proteins were all up-regulated in the CWP group compared to the healthy subjects except creatine kinase which was down-regulated. This could be explained by a higher dependence and therefore a higher strain on the glycolysis to provide energy for the skeletal muscle resulting in an accumulation of Pi, H+, pyruvate and lactate.

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