Figure 2

Functional connectivity during the ACE task.

Global broadcasting of information across distant cortical regions (wSMI). Two tail t-test on the wSMI matrices of each group were obtained by subtracting the correlation matrices of the incongruent and congruent conditions. The Frequency Specificity Graph shows the sensitivity of wSMI to pure-frequency signals. The value of τ makes the wSMI measure sensitive to different frequency ranges (τ = 4 ms is specific for frequencies among 11–40 Hz and τ = 32 ms is specific for frequencies ranging between 1 and 11 Hz). (A) Analysis for tau 4 ms (>11 Hz): (i) histogram showing the number of occurrences (y axis) of the t values (x axis); the distribution of these values exhibits a positive trend, indicating that information sharing is larger for controls than EPD patients; (ii) correlation matrix of raw T value; (iii) masked correlation matrix: T values were corrected with an alpha level set at p < 0.01; non-significant values were assigned a 0; (iv) connectivity map of significant connections only across the scalp indicating that controls presented higher information sharing at frontotemporal regions. (B) Analysis for tau 32 ms (specific for 1–11 Hz): (i) histogram showing the number of occurrences (y axis) of the t values (x axis); the distribution of these values exhibits a positive trend, indicating that information sharing is larger for controls than EPD patients; (ii) correlation matrix of raw T value; (iii) masked correlation matrix: T values were corrected with an alpha level set at p < 0.001; non-significant values were assigned a 0; (iv) connectivity map of significant connections only across the scalp indicating that controls presented higher information sharing mainly at bilateral temporal regions.