Table 1 Characteristics of included studies.

From: Esophageal Squamous Cell Carcinoma and Gastric Cardia Adenocarcinoma Shared Susceptibility Locus in C20orf54: Evidence from Published Studies

Author

Year

Study type

Ethnicity (Country)

Cancer type

Source of control

Genotyping

Matching Y/N

Sample size Case/Control

Qualitya control

P HWE

Peng[15]

2014

Case-control

Asian (China)

ESCC

Population

Sequenom

N

50/50

N

NA

Peng[15]

2014

Case-control

Asian (China)

GCA

Population

Sequenom

N

50/50

N

NA

Piao [16]

2014

Case-control

Asian (Korea)

ESCC

Population

HRM

Y

321/1700

Y

0.724

Gu [17]

2012

Case-control

Asian (China)

ESCC

Hospital

MassArray

Y

379/375

Y

0.648

Wei [18]

2012

Case-control

Asian (China)

ESCC

Population

PCR-RFLP

Y

240/198

Y

0.354

Dura [19]

2012

Case-control

Caucasian (Netherland)

ESCC

Population

Real-Time PCR

Y

344/580

N

0.267

Zhou [20]

2012

Case-control

Asian (China)

ESCC

Population

Chips

Y

4722/4732

Y

0.639

Ren [21]

2011

Case-control

Asian (China)

GCA

Population

Chips

Y

2748/10136

Y

0.407

Shang [22]

2011

Case-control

Asian (China)

ESCC

Population

MALDI-TOF-MS

Y

190/211

N

0.336

Zhang [23]

2011

Case-control

Asian (China)

GCA

Population

TaqMan

Y

1668/1841

Y

0.284

Wang [10]

2010

GWAS

Asian (China)

ESCC

Population

Chips

Y

9053/13283

Y

NA

Wang [10]

2010

GWAS

Asian (China)

GCA

Population

Chips

Y

2766/11013

Y

NA

  1. ESCC, Esophageal squamous cell carcinoma; GCA, Gastric cardia adenocarcinoma; NA: Not applicable for the lack of C allele;
  2. HRM, High-resolution melting; MALDI-TOF-MS, Matrix-Assisted Laser Desorption/Ionization Time of Flight Mass Spectrometry;
  3. aQuality control was conducted when sample of cases and controls was genotyped.