Table 3 Main results of pooled ORs in the meta-analysis.

From: Esophageal Squamous Cell Carcinoma and Gastric Cardia Adenocarcinoma Shared Susceptibility Locus in C20orf54: Evidence from Published Studies

 

Cases

Controls

Heterogeneity test

 

Hypothesis test

 

Comparisons

n/N

n/N

Q

P

I2(%)

Summary OR (95% CI)

Z

P

Studies

Total

T vs C

10039/36106

23195/79834

10.32

0.33

13

0.95(0.92,0.97)

3.74

<0.01

10

CT vs CC

4304/9515

8381/17945

9.68

0.21

28

0.94(0.88,0.99)

2.04

0.04

8

TT vs CC

953/6308

1820/11536

8.57

0.29

18

0.91(0.83,0.99)

2.08

0.04

8

CT + TT vs CC

5306/10712

10115/19865

9.25

0.41

3

0.94(0.89,0.99)

2.50

0.01

10

TT vs CT + CC

953/10612

1820/19765

9.92

0.19

29

0.93(0.86,1.02)

1.55

0.12

8

ESCC

T vs C

8444/29922

16973/58402

6.90

0.33

13

0.95(0.90,0.99)

2.24

0.02

7

CT vs CC

2416/6140

2657/7147

7.21

0.21

31

0.95(0.89,1.03)

1.24

0.22

6

TT vs CC

489/3780

649/4706

3.21

0.67

0

0.91(0.80,1.04)

1.38

0.17

6

CT + TT vs CC

2931/6246

3768/7846

4.38

0.63

0

0.95(0.88,1.02)

0.49

0.14

7

TT vs CT + CC

489/6196

649/7796

5.87

0.32

15

0.94(0.83,1.07)

0.96

0.34

6

GCA

T vs C

1595/6584

6222/21432

3.42

0.18

42

0.95(0.91,0.98)

3.00

<0.01

3

CT vs CC

1888/3375

5724/10798

2.25

0.13

55

0.93(0.85,1.01)

1.69

0.09

2

TT vs CC

464/2582

1171/6830

5.35

0.02

81

0.93(0.69,1.26)

0.45

0.65

2

CT + TT vs CC

2375/4466

6347/12019

4.75

0.09

58

0.93(0.87,1.00)

2.00

0.05

3

TT vs CT + CC

464/4416

1171/11969

4.02

0.05

75

0.93(0.82,1.05)

1.22

0.22

2

Back to article page