Figure 7

Correlation analysis of urinary and renal metabolites.

Pearson’s correlations of UACR and quantities of the metabolites determined from 17-week-old mice urine samples (A, wildtype mice; B, db/db mice) and kidney samples (C, wildtype mice; D, db/db mice). Red and blue represent positive and negative correlations, respectively, the colour scale represents Pearson’s correlation coefficients. Keys: UACR, urinary albumin to creatinine ratio; LAC, lactate; PYR, pyruvate; SUCC, succinate; 2-OX, 2-oxoglutarate; CIT, citrate; C-AC, cis-aconitate; FUM, fumarate; Ma, methylamine; DMA, dimethylamine; TMA, trimethylamine; ACE, acetate; 3-HB, 3-hydroxybutyrate; AC, acetone; ACA, acetoacetate; CRE, creatine; CRT, creatinine; ALLA, allantion; HIP, hippurate; MNA, 1-methylnicotinamide; 3-IS, 3-indoxylsulfate; FOR, formate; ALA, alanine; PHE, phenylalanine; CHO, choline; M-INS, myo-inositol; GLU, glutamate; GLY, glycine; TYR, tyrosine; TAU, taurine; ASP, aspartate; VAL, valine; LEU, leucine; ILE, isoleucine; URA, uracil; URI, uridine; GTP, guanosine triphosphate; NIA, niacinamide.