Figure 1 | Scientific Reports

Figure 1

From: Promoter-level expression clustering identifies time development of transcriptional regulatory cascades initiated by ErbB receptors in breast cancer cells

Figure 1

(a) The signal transduction pathway activated upon stimulation of MCF-7 cells by HRG or EGF. (b) Comparison of MAPK proteins abundance after the stimulation of the same ligands (10 nM) by HRG (black pattern) and EGF (red pattern), quantified by Western blot analysis. (c) Comparison of MAPK proteins phosphorylation levels after the stimulation of the same ligands (10 nM) by HRG (black pattern) and EGF (red pattern), quantified by Western blot analysis. Western blot experiments were performed twice. Each dot in panels a and b represents the quantified values in an independent experiment and lines represent the average of these values.

Back to article page