Figure 7
From: MitoRCA-seq reveals unbalanced cytocine to thymine transition in Polg mutant mice
The context dependency of C → T transitions identified in mouse mtDNAs
(A) The frequency of 16 all possible trinucleotides, in which the middle nucleotide is subject to C to T transition. The ratio of ‘TCA’ and ‘NCN’ trinucleotides found in the mouse mitochondrial genome is shown as a dashed line. ‘N’ denotes any nucleotide. (B) The percentage of ‘TCA’ trinucleotides in the mouse mitochondrial genome that contain a C → T transition in different samples.
