Figure 1 | Scientific Reports

Figure 1

From: Regulation rewiring analysis reveals mutual regulation between STAT1 and miR-155-5p in tumor immunosurveillance in seven major cancers

Figure 1

Regulatory activity of TF and miRNA in cancers.

The correlation patterns of four regulation types across the seven TCGA cancer types. The regulation types are labeled on the right-hand side. For each cancer type, the percentage of positive and negative regulations is shown as a function of the top 1% to 10% and 100% correlated GRNs. In each cancer type, the left and right sub-column represents the correlated GRN derived from normal and tumor samples, respectively. The asterisk shows the enrichment significance of positive or negative regulations with P < 0.05, as produced by Fisher′s exact test. The red (green) asterisks indicate that the positive (negative) regulations are significantly overrepresented.

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