Table 3 Cumulative effect of TNF/TRAF2/ASK1/p38 kinase signaling pathway variants on lung complications risk.

From: Genetic variation in the TNF/TRAF2/ASK1/p38 kinase signaling pathway as markers for postoperative pulmonary complications in lung cancer patients

# of Risk Genotypes

Event, N(%)

No Event, N(%)

aOR(95%CI)

P-value

0 to 2

41(23.84%)

131(76.16%)

1(reference)

 

3

56(38.89%)

88(61.11%)

2.10(1.23–3.59)

6.46 × 10−8

4 to 5

97(48.50%)

103(51.50%)

3.95(2.40–6.50)

6.10 × 10−8

P for trend

1.63 × 10−8

   
  1. aAdjusted for age at surgery, gender, intra-operative transfusion, % DLCO predicted and chest wall resection.
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