Table 1 Clinical and echocardiographic characteristics: comparison between Non-Sarcopenia and Sarcopenia groups.

From: Fetuin-A as a predicator of sarcopenic left ventricular dysfunction

 

Non-Sarcopenia (n = 449, 82.9%)

Sarcopenia (n = 92, 17%)

p-value

Age (years)

75 ± 5

79 ± 6

0.001*

Male (%)

251 (55.9)

32 (34.7)

0.001*

WC (cm)

88.63 ± 9.77

78.73 ± 8.74

0.001*

BMI (kg/m2)

25.3 ± 3.9

22.37 ± 3.1

0.001*

SBP (mmHg)

135.6 ± 20.8

128.5 ± 19.2

0.003*

DBP (mmHg)

77.7 ± 11.7

73.6 ± 11.3

0.002*

Medical History (%)

 CKD

76 (16.9)

45 (48.9)

0.001*

 Previous stroke

17 (3.7)

3 (3.2)

0.89

 CAD

11 (2.4)

2 (2.2)

0.8

 Arrhythmia

19 (4.1)

2 (1.6)

0.8

 Cancer

11 (2.4)

4 (3.3)

0.37

Serology profiles

 HbA1c (%)

6.1 ± 0.9

6.1 ± 1.1

0.79

 TG (mg/dl)

128.6 ± 79.5

113.8 ± 58.2

0.1

 Cholesterol (mg/dl)

201.3 ± 36.7

204.1 ± 34.6

0.52

 HDL-C (mg/dl)

49.8 ± 12.4

54.4 ± 15.4

0.003*

 Total bilirubin (mg/dl)

0.63 ± 0.3

0.61 ± 0.55

0.67

 FetA (μg/ml)

621.1 ± 140.7

697.3 ± 179.6

0.0001*

 Echocardiographic parameters

 LVMI (g/M2)

81.9 ± 20.4

84.2 ± 30.2

0.65

 LVEF (%)

68.79 ± 8.6

62.64 ± 9.3

0.007*

 E/A

0.79 ± 0.23

0.67 ± 0.32

0.14

 E′ (m/s)

0.09 ± 0.03

0.075 ± 0.02

0.08

 E/E′

7.5 ± 2.1

9.2 ± 4.4

0.001*

  1. Data are n (%) or mean ± standard error. BMI = body mass index; BW = body weight; CAD = coronary artery disease; CKD = chronic kidney disease (defined by eGFR ≤60 ml/min/1.73 m2); DBP = diastolic blood pressure; E/A = peak early filling velocity (E) to peak atrial velocity (A) ratio; E/E’ = early mitral inflow velocity to early annular diastolic velocity ratio; FetA = fetuin-A; HbA1C = glycated hemoglobin; HDL-C = high-density lipoprotein cholesterol; LVEF = left ventricular ejection fraction; LVMI = left ventricular mass index; SBP = systolic blood pressure; TG = triglycerides; WC = waist circumference.
  2. *p < 0.05.
Back to article page