Figure 1 | Scientific Reports

Figure 1

From: Regulation of T cell function by microRNA-720

Figure 1

HBV-specific CD8+ T Cells in the Spleens of CHB Patients.

(a) The frequencies of HBV core antigen 18-27 epitope pentamer-positive CD8+ T cells among PBMCs, splenocytes and liver cells from CHB patients were detected by flow cytometry (n = 6, 5 and 6 respectively). Bar indicates mean. (b) IFN-γ production by HBV-specific T cells from the spleens of CHB patients was detected by ELISPOT. (c) Frequency of HBV-specific CD8+ T cells after 6 days of culture with PBS or HBV core antigen protein (n = 4 and 4). A two-tailed Student’s t-test was used to determine significance. **p < 0.01; ***p < 0.001; NS, Not Significant.

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