Figure 5
TGFβ and TCR Signaling Promote miR-720 Expression.
(a) Cytokine profile of plasma from CHB patients (Luminex assay; n = 10 and 12 respectively). (b) TGFβ levels in the plasma from CHB patients and healthy control donors (HC) (n = 8 and 12). (c) miR-720 expression levels in resting and activated CD8+ T cells with or without anti-CD3, anti-CD28, or TGFβ. Data are representative of four independent experiments (n = 4 and 4). Data are represented as mean ± SEM in (a) and (c). Bar indicates mean in (b). Two-tailed unpaired (b) and paired (c) Student’s t-tests were used to determine significance. *p < 0.05; **P < 0.01.
