Figure 3
From: Computational Prediction and Validation of BAHD1 as a Novel Molecule for UlcerativeColitis
Reduced BAHD1 expression in in vivo and in vitro models and inUC patients.
(A) Nuclear localization of BAHD1 in normal human large intestine.Histological sections of colon samples taken from healthy adjacent ordistant colon from subjects of certain human cancers were stained for BAHD1.Magnification of 10*10 (upper) and 10*40 (lower) show that BAHD1 (brownstaining) is universally present in IECs and crypt cells in the largeintestine. (B) IHC for BAHD1 in UC patient colonic tissue (lower)compared with the control group (upper), 10*20 magnification. (C)Western blot analysis of BAHD1 expression in vitro and invivo. The blots shown represent at least three independent experiments;GAPDH was used as a loading control.
