Figure 7
From: Computational Prediction and Validation of BAHD1 as a Novel Molecule for UlcerativeColitis
BAHD1 modulated the TNF signalling pathway by altering TNFR1expression.
Caco-2 cells were incubated with BAHD1 siRNA (siBAHD1) and a negative controlsiRNA (NC) before incubation with the mixture (Mix) for 24 h tomimic gut inflammation. (A) mRNA and (B) protein levels showedsignificantly increased contents of TNFR1 in the siBAHD1 group compared withthe NC group. (C) A hypothesis regarding BAHD1 negative regulation ofthe TNF signalling pathway. The data are expressed as themean ± SEM;n = 3, *p < 0.05;**p < 0.001 versus NC group. For the blots,independent experiments were repeated at least three times.
