Table 3 The influence of CTV displacement estimation on PTV coverage and OAR sparing.

From: Dosimetric Comparison and Evaluation of Three Radiotherapy Techniques for Use after Modified Radical Mastectomy for Locally Advanced Left-sided Breast Cancer

Organ at risk

Parameters

3DCRT-FinF -PTV0.7 cm

3DCRT-FinF -PTV0.5 cm

p

PTV

V 95%

78.23 ± 4.25

56.94 ± 5.62

 < 0.001

Heart

D mean

7.29 ± 3.05

3.80 ± 2.20

 < 0.001

V 5Gy

22.14 ± 8.64

9.40 ± 6.47

 < 0.001

V 10Gy

14.95 ± 6.74

6.83 ± 5.21

 < 0.001

V 20Gy

12.48 ± 6.36

5.36 ± 4.44

 < 0.001

V 30Gy

10.74 ± 5.89

4.24 ± 3.68

 < 0.001

Left lung

D mean

15.32 ± 2.72

10.91 ± 2.75

 < 0.001

V 5Gy

49.63 ± 7.76

35.97 ± 8.40

 < 0.001

V 10Gy

37.52 ± 7.10

25.63 ± 6.95

 < 0.001

  1. p:3DCRT-FinF-PTV0.7 cm (3DCRT-FinF plans generated from PTV0.7 cm with presumably accurate estimation of CTV displacement of 0.7 cm) & 3DCRT-FinF-PTV0.5 cm (3DCRT-FinF plans generated from PTV0.5 cm with underestimation of CTV displacement, presuming that the actual CTV displacement valuation was 0.7 cm). Data presented as mean ± standard deviation. p-values from paired-sample t test.
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