Figure 2 | Scientific Reports

Figure 2

From: Bioresponsive antisense DNA gold nanobeacons as a hybrid in vivo theranostics platform for the inhibition of cancer cells and metastasis

Figure 2

(A) Epi-fluorescence analysis of nude mice bearing orthotopic human gastric cancer cells, 0.5, 4, 24, 72 and 120 hours after tail-vein injection of nonsense (50 nM) and anti-Kras (5 and 50 nM) nanobeacons. Arrows represent gastric tumors. (B) Epi-fluorescence images of whole body organs to evaluate selective signal from the gold nanobeacons accumulated in tumors. (C) Quantification of anti-Kras nanobeacons signal in the region of interest (ROI) in major organs (liver, kidney, spleen, heart, lung and tumor) at 5 days after nanobeacons injection.

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