Figure 3 | Scientific Reports

Figure 3

From: Therapeutic potential of digitoflavone on diabetic nephropathy: nuclear factor erythroid 2-related factor 2-dependent anti-oxidant and anti-inflammatory effect

Figure 3

Activation of Nrf2 by digitoflavone improves metabolic disorder in a STZ-induced diabetic model.

(A) The average level of blood glucose (4h fast) in each animal group is plotted. (B) Body weights of Nrf2+/+ (left panel) and Nrf2−/− (right panel) animals are shown. (C) Urine output from Nrf2+/+ (top panel) and Nrf2−/− (bottom panel) animals is shown. (D) Water consumption in the last 24 h before the mice were sacrificed is reported. (E) Blood insulin content is shown. Data are expressed as mean ± SD (n = 5). *P < 0.05 vs. control mice. **P < 0.01 vs. control mice. #P < 0.05 vs. STZ mice.

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