Figure 4 | Scientific Reports

Figure 4

From: Therapeutic potential of digitoflavone on diabetic nephropathy: nuclear factor erythroid 2-related factor 2-dependent anti-oxidant and anti-inflammatory effect

Figure 4

Digitoflavone alleviates renal damage induced in the STZ-diabetic model.

(A) Kidney-to-body weight ratios are provided. (B) and (C) Serum creatinine and BUN content is reported. (D) and (E) Albuminuria was assessed by measuring UAE (D) and UACR (E). Kidney tissue sections from each mouse were subjected to HE, PAS and trichrome staining. (F) A representative image from 1 mouse per group is shown. G: PAS-stained tissues were used for semiquantitative scoring to obtain the glomerulosclerotic index. Data are expressed as mean ± SD (n = 5). *P < 0.05 vs. control mice. **P < 0.01 vs. control mice. #P < 0.05 vs. STZ mice.

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