Table 2 List of serum miRNAs significantly (p < 0.001) overexpressed in NSCLC versus NC that were up-regulated as well in lung adenocarcinoma (AC) or squamous cell carcinoma (SCC) primary tumors as compare to nonmalignant lung tissue (NL).
From: A Novel Serum 4-microRNA Signature for Lung Cancer Detection
miRNA | AUC stage I | Serum NSCLC/NC | Lung AC/NL | Lung SCC/NL | High expression in blood cells | Reported in NSCLC | Reported in other cancers |
|---|---|---|---|---|---|---|---|
miR-141 | 0.875 | up | up | up | no | no | 18663219; 23935962 |
miR-193b | 0.855 | up | up | up | NA | no | 24778027 |
miR-200b | 0.849 | up | up | up | no | no | 23272653; 20551052 |
miR-301 | 0.841 | up | up | NS | NA | 20595154 | no |
let-7g | 0.840 | up | NS | up | NA | no | 24709885 |
miR-331 | 0.748 | up | NS | up | NA | no | 21035526 |
miR-758 | 0.747 | up | up | NA | NA | no | no |
miR-744 | 0.726 | up | up | NA | NA | no | 22432036 |
miR-106a | 0.958 | up | NS | up | yes | 21544802 | 20234369; 25140035 |
miR-19a | 0.948 | up | up | NS | yes | no | no |
miR-17 | 0.918 | up | NS | up | yes | no | 23056289 |
miR-19b | 0.916 | up | NS | up | yes | no | 23874370; 24498016 |
miR-93 | 0.899 | up | NS | up | yes | no | 23748853; 24498016 |
miR-20b | 0.875 | up | NS | up | yes | 20595154 | no |
miR-106b | 0.838 | up | up | up | yes | no | 20234369; 23874370 |
miR-215 | 0.828 | up | up | NS | yes | no | 22353773; 24993656 |
miR-25 | 0.826 | up | NS | up | yes | no | 24595006; 24651474 |
miR-200c | 0.820 | up | up | up | yes | no | 22954417; 23272653 |
miR-93* | 0.739 | up | up | NA | yes | no | no |
miR-24 | 0.715 | up | NS | up | yes | no | 23697990 |
