Figure 6
From: Mieap suppresses murine intestinal tumor via its mitochondrial quality control
Higher tumor cell proliferative potentials in the intestinal adenomas and adenocarcinomas of the ApcMin/+ Mieap+/− and ApcMin/+ Mieap−/− mice.
Small intestinal (a) and colonic (b) tumor cell proliferative potentials in the ApcMin/+, ApcMin/+ Mieap+/− and ApcMin/+ Mieap−/− mice (n = 8, each) were histopathologically evaluated by Ki67 labeling indices (%), which indicated statistically significant increases in the high-grade adenomas (Category 2) and adenocarcinomas (Category 3) in the ApcMin/+ Mieap+/− and ApcMin/+ Mieap−/− mice compared to the ApcMin/+ mice. The data represent the mean Ki67-labeling indices ± SD (*P < 0.05; **P < 0.01; ***P < 0.001; ****P < 0.0001).
